Dr.

Dian R

Struktur Kulit dan Jaringan

Subkutan
Organ terbesar menutupi are 1.5-2 m2 15% BB
2 lapisan
- stratified squamous epithelium - epidermis

- deeper connective tissue layer dermis

hypodermis
1 - 2 mm (kelopak mata -- bahu)
Tebal-tipis epidermis (stratum korneum)
Hanya kelenjar keringat

Epidermis
Epitel pipih berlapis

berkeratin
Ujung saraf
4 zona (5)
Avascular

Stratum Basale
Selapis epitel sel kuboid/

low columnar epithel

3 tipe
1. keratinosit
2. Melanosit
3. Sel Merkel

Stratum Spinosum

Keratinosit
Sel dendritik
desmosom

Stratum Granulosum
2- 3 lapis keratinosit pipih(> tebal
kerato-hyalin granule
membrane-coating vesicles

Stratum Lucidum
Lapisan transluscent (tebal)
Eleidin
Tidak ada nukleus/organel

Stratum Corneum
30 lapis sel keratinosit mati

Stratum corneum

Stratum lucidum
Stratum granulosum
Stratum spinosum

Stratum basale

Dermis
0.2-4 mm
Serabut kolagen, elastin, retikuler
Pembuluh darah, kelenjar keringat, kelenjar sebasea,

folikel rambut dan akar kuku

Ujung saraf sensorik jaringan otot
Papilla dermal area sensitive

 2 lapisan
Lapisarn papiler jaringan ikat areolar -- imun
Lapisan retikuler jaringan ikat padat

Reseptor sensorik kulit

Meissner's corpuscle
Free nerve ending

Pacinian corpuscle

Hair follicle receptor

(root hair plexus)

Spinal cord

Histology

External Internal

hipodermis
Jaringan subkutan, fasia superfisial
Reservoar energi, insulator

Skin Color
Hemoglobin
Melanin
Karoten

Fungsi
Barier
Sintesis vit D
Fungsi sensorik

Termoregulasi

Rambut
Organ asesoris
Keratin keras ikatan disulfida
Pillus pili

Filamen tipis sel keratin

Folikel
Hampir di seluruh tubuh

Struktur Rambut dan Folikel

3 jenis : lanugo, velus, rambut tipe terminal
3 zona
1. Bulb
2. Akar
3. shaft
Papil
3 lapisan
1. Medulla
2. Korteks
3. kutikula

Hair Bulb
Hair Shaft
(visible hair)
Hair Root
(embedded)

Folikel
Tabung diagonal tertanam dlm

dermis hipodermis
2 lapisan
epithelial root sheath
connective tissue root sheath.
Serat saraf dan otot
Stem cell

Hair Root

Hair
Follicle

Hair Bulb

Hair
Papilla

Hair
follicle

(smooth muscle)

Sebaceous (oil) gland

Kuku
Sel keratin
1 mm/mig

Kelenjar keringat
Merokrin(ekrin)
Apokrin
Kelenjar tubulus sederhana
Duktus: sel epitel kuboid berlapis(dermis)

keratinosit(epidermis)
Sel mioepitel -- parasimpatis

Sweat Glands

Sudoriferous (sweat)
glands
Cross section

Low magnification

High magnification

Kelenjar sebasea