DAFTAR ISI

Halaman
DAFTAR ISI

PENDAHULUAN

ii

BAB
1 TINJAUAN PUSTAKA .............................................................................................1
1.1 Ayam Broiler ........................................................................................................1
1.2 Penyakit Yang Ditimbulkan Akibat Infeksi Bakteri Pada Ayam Broiler ...............3
1.3 Penggunaan Sulfadiazin-Trimetoprim dalam Peternakan ....................................11
1.4 Pengaruh Residu .................................................................................................11
2 METODE PENELITIAN ..........................................................................................13
3 BAHAN DAN ALAT ...............................................................................................14
3.1 Bahan ..................................................................................................................14
3.2 Alat .....................................................................................................................14
4 RANCANGAN KERJA ...........................................................................................15
4.1 Penyiapan Kandang
4.2 Pemilihan Obat Kombinasi....................................................................................15
4.3 Pembuatan Sediaan Tunggal.................................................................................15
4.4 Pemeriksaan Sediaan ..........................................................................................15
4.5 Validasi Metode Analisis

..................................................................................15

4.6 Pemberian Sulfadiazin dan Kombinasi Sulfadiazin-Trimetoprim Rute Oral

dan Intravena .......................................................................................................15
4.7 Pengambilan Sampel Darah dan Penyimpanan ...................................................16
4.8 Pembuatan Kurva Kalibrasi
4.9 Preparasi Sampel .................................................................................................16
4.10
Analisis Kadar Sulfadiazin dalam Sampel Plasma Menggunakan HPLC
Detektor UV .........................................................................................................16
5 PERENCANAAN KEGIATAN DAN KENDALA
6 ANGGARAN DANA .................................................................................................17
DAFTAR PUSTAKA ......................................................................................................23