Biosintesis Terpenoid

Jalur Non Mevalonat

Oleh:
Akmel Suhada (20519301)
Ana Yulvia (20519306)
Lailatul Musyarrofah (20519309)
Irhami Kurnia (20519321)
 Jalur Biosintesis Terpenoid
Metabolisme Glikolisis

Glikosa

Gliceraldehyde 3
Jalur prekusor phospate
MEP
(metylerythritol
phospate)
Pyruvate

Jalur prekuser
MVA (mevalonat
Acetyl Co-A
acid

Creb Cycle
 Jalur Biosintesis Terpenoid
Jalur Biosintesis Terpenoid
NO Perbedaan
MVA MEP

1 Tempat Terjadinya Sitosol dan Mitokondria Plastida

2 Prekusor Asetil Co-A Piruvat dan Gliseraldehid 3 fosfat

7 Enzim : DXPS, DXR, CD-ME synthase,

5 Enzim : AACT, HMGS,
3 Enzim CDP-ME kinase, MECP synthase, HMBPP
HMGR, PMK, MDC
synthase, HMBPP recdutase

Terpenoid sterol, Monoterpen, diterpen, hemiterpen,

Senyawa yang
4 sesquiterpen, poliphenol, karotenoid, asam absiat, dan rantai ftol
dihasilkan
ubiquinon, pada klorofil
Perbandingan Jalur MVA dan MEP
Bukti Jalur Biosintesis
 Daftar Pustaka
 Dewick, P. M. (2002). Medicinal natural products: a
biosynthetic approach. John Wiley & Sons.

 Tholl, D. (2015). Biosynthesis and biological functions of

terpenoids in plants. In Biotechnology of isoprenoids (pp.
63-106). Springer, Cham.

 Yamazaki, Y., Kitajima, M., Arita, M., Takayama, H., Sudo, H.,
Yamazaki, M., ... & Saito, K. (2004). Biosynthesis of
camptothecin. In silico and in vivo tracer study from [1-
13C] glucose. Plant physiology, 134(1), 161-170.