Diazepam
Injeksi (i.m./i.v.)
Tiap ml mengandung:
Diazepam ................................................................... 5 mg
FARMAKOLOGI
VALISANBE mengandung Diazepam yang mempunyai
efek kerja spesifik pada behavioural system di otak.
Diazepam juga berkhasiat menenangkan mental,
menstabilkan saraf otonom dan menimbulkan efek hipnotik-sedatif.
VALISANBE juga memiliki efek merelaksasi otot, sehingga sangat berguna pada pengobatan penyakitpenyakit muskuloskeletal.
INDIKASI
Keadaan neurotik, keadaan psikosomatik, gejala-gejala
withdrawal alkohol, status epileptikus dan pra operasi.
KONTRA-INDIKASI
Glaukoma, miastenia gravis, penderita yang hiper-sensitif
terhadap Diazepam, penderita keadaan koma, syok,
intoksikasi, alkohol akut dengan tanda-tanda vital depresi.
EFEK SAMPING
Rasa mengantuk, ataksia, depresi pernapasan, tremor,
vertigo, konstipasi, kesukaran berbicara.
PERHATIAN
Penderita yang telah diberi injeksi Diazepam, sebaiknya
tidak melakukan pekerjaan berbahaya yang memerlukan kewaspadaan mental penuh seperti mengendarai
kendaraan dan bekerja dengan mesin-mesin yang
berbahaya. Hati-hati bila digunakan pada penderita
dengan gangguan hati. Pemberian preparat parenteral
pada penderita usia lanjut atau penderita yang menerima obat-obat depresan saraf pusat atau penderita
dengan gangguan pulmonari harus dengan sangat hatihati karena ada kemungkinan timbulnya apnea, depresi
pernapasan atau cardiac arrest.
Hindari penggunaan pada wanita hamil trimester pertama.
Hindari penggunaan jangka panjang karena dapat
menimbulkan ketergantungan fisik dan psikis.
KEMASAN
Dus, isi 10 ampul @ 2 ml.
No. Reg.: DPL8722202343A1
PENYIMPANAN
Simpan di tempat sejuk (15 - 25 C), terlindung dari cahaya.
Dibuat oleh: PT SANBE FARMA
Bandung - Indonesia
BF 443 - 1
VALISANBE
Diazepam
Injection (i.m./i.v.)
Each ml contains:
Diazepam ................................................................... 5 mg
PHARMACOLOGY
VALISANBE contains Diazepam which has a specific
and selective action on the behavioural system of the
brain. It has mental relaxing, autonomic stabilizing, and
sedative-hypnotic effects.
VALISANBE has also a muscle relaxing effect which
makes it particularly valuable in the treatment of musculoskeletal disorders.
INDICATIONS
Neurotic states, psychosomatic states, alcohol withdrawal symptoms, status epilepticus, pre-operative
conditions.
CONTRA-INDICATIONS
Glaucoma, myasthenia gravis, patients with a known
hypersensitivity to Diazepam, patient in coma condition,
shock, acute alcohol intoxication with depresion as a
symptom.
ADVERSE REACTIONS
Drowsiness, ataxia, pulmonary depression, tremor,
vertigo, constipation, slurred speech.
PRECAUTIONS
Patients receiving Diazepam, should be cautioned
against engaging in hazardous occupations requiring
complete mental alertness, such as operating machinery or driving a motor vehicle. Use with caution in
patients with liver dysfunction. Extreme care must be
given when administering Diazepam injection, particularly by the parenteral administration, to the elderly
or patients which are receiving CNS depressant or in
patients with limited pulmonary reserve because of the
possibility that apnea, pulmonary depression or cardiac
arrest may occur.
Avoid using this drug during the first trimester of pregnancy.
Avoid the long term use because it may cause psychological and physical dependence.
It should be used with caution in patient receiving CNS
depressant drugs and alcohol.
There are no negative effects in lactating women as
long as the dose is not higher than 10 mg.
DRUG INTERACTIONS
- Diazepam should be used with caution in concomitant
with anticoagulant since it may inhibit the effect of
anticoagulant but it has not been clinically established.
- Concomitant use with muscle relaxation drug may
decrease the relaxation effect.
DOSAGES
Status Epilepticus
- Adults:
5 mg to 10 mg and may be repeated if necessary at 10
to 15 minutes interval up to a maximum dose of 30 mg.
- Children 5 years or older:
1 mg slowly every 2 to 5 minutes up to a maximum of 10
mg.
- Infants over 30 days of age & children under 5 years:
0.2 to 0.5 mg slowly every 2 to 5 minutes up to a
maximum of 5 mg.
The drug may be given intramuscularly whenever intravenous administration is not possible.
Tetanus or severe muscle spasm
- Adults:
5 mg to 10 mg and may be repeated in 3 to 4 hours, if
necessary.
- Children:
1 mg to 2 mg slowly repeated every 3 to 4 hours if
necessary.
ON MEDICAL PRESCRIPTION ONLY
PRESENTATIONS
Box of 10 ampoules @ 2 ml.
Reg. No.: DPL8722202343A1
STORAGE
Keep in a cool place (15 - 25C), away from light.
Manufactured by: PT SANBE FARMA
Bandung - Indonesia
BF 443 - 1