NPM :2017210177
The Saga Leaf (Abrus Precatorius L) is a medicinal plant, which is used by Indonesians and
is commonly used as a symbol of affection but there are reports of the process used as
jewelry. In addition, Saga Leaf is known to have anti-asthma properties because it is proven
to The effect of Abrus precatorius (EAPL) leaf ethanol extract on albumin eggs induced mast
cell degranulation in rats and passive cutaneous anaphylaxis in rats by using Abrus
precatorius leaf ethanol extract (EAPL) at a dose of 100, 125,150 mg / kg ip evaluated for
initial phytochemical screening. Acute toxicity studies and albumin eggs induce mast cell
degranulation in mice and passive cutaneous anaphylaxis in mice. Thus, the current results
indicate that the LD50 EAPL is more than 1300 mg / kg. EAPL (100-150 mg / kg, i.p.)
significantly protects albums of eggs induced by mast cell degranulation and inhibits the area
of dye leakage in passive cutaneous anaphylaxis. Study of phytochemical leaves tion of
saponins, alkaloids, flavonoids, and glycosides. Conclusion: In conclusion EAPL has the
potential for anti-asthma.