PERHITUNGAN

MATEMATIKA ZAT PADAT

Dyah Rahmasari, M.Farm., Apt.
 CONTOH 1

Dalam resep dibutuhkan 3 tablet metronidazol 500 mg untuk

dimasukkan ke dalam 5 buah kapsul.

Pertanyaan :
a.Berapakah mg metronidazol dalam tiap-tiap kapsul ?
b.Jika tersedia metronidazol tablet 250 mg, berapa tablet yang
harus diambil ?

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Jawaban
1 tablet mengandung 500 mg
Dibutuhkan 3 tablet
Jadi : 3 x 500 mg = 1500 mg

a. Akan dibuat 5 kapsul

1500 mg/ 5 kapsul = 300 mg
Jadi tiap kapsul mengandung 300 mg metronidazol
b. Jika yang tersedia 250 mg
1500 mg/250 mg = 6 tablet

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 CONTOH 2

Paracetamol 500 mg 5
CTM 4 mg 5
mf pulv No VIII
Pertanyaan :
S 3 dd 1 a.Jika paracetamol yang tersedia
hanya 250 mg. Berapa tablet
Pro : Ariana (8 th) paracetamol yang dibutuhkan?
b.Berapa kandungan paracetamol
dan CTM dalam masing-masing
pulveres?

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Jawaban
Diketahui :
Paracetamol 500 mg sebanyak 5 tablet
CTM 4 mg sebanyak 5 tablet
a. Tersedia PCT 250 mg
500 mg x 5 tablet = 2500 mg
2500 mg/250 mg = 10 tablet
b. PCT 5 tab x 500 mg = 2500 mg
PCT dalam tiap bungkus : 2500 mg/8 = 312,5 mg
CTM 5 tab x 4 mg = 20 mg
CTM dalam tiap bungkus : 20 mg/8 = 2,5 mg
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 CONTOH 3

Setiap hari Nn. Prilly harus meminum Zantac 150 mg b.i.d.

selama 15 hari. Namun Zantac yang tersedia adalah 300 mg.
Berapa Zantac yang harus diambil?

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Jawaban
Diketahui :
Zantac 150 mg 2 kali sehari selama 15 hari.

Pemakaian 1 hari : 150 mg x 2 = 300 mg

Pemakaian 15 hari : 300 mg x 15 = 4500 mg
Zantac yang dibutuhkan sebanyak
= 4500 mg
300 mg
= 15 tablet

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 CONTOH 4

Paracetamol 500 mg 5
CTM 4 mg 4
Pertanyaan :
Vit C 250 mg 5 a.Jika diketahui berat tablet PCT :
mf caps no VII 700 mg, CTM : 100 mg; dan vit C
S 3 dd1 cap 1
350 mg. Berapa berat tiap
kapsul?
Pro : Camila(15 th)
b.Berapa kandungan masing-
masing obat dalam tiap kapsul?

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Jawaban
a. Berat PCT = 700 mg x 5 tab= 3500 mg
Berat CTM = 100 mg x 4 tab = 400 mg
Berat Vit C = 350 mg x 5 tab= 1750 mg
Berat serbuk per kapsul:
3500 mg+400 mg+1750mg
7
= 807.14 mg
b. PCT = 500 mg x 5 tab= 2500 mg/7 =357, 1 mg
CTM = 4 mg x 4 tab= 16 mg/7= 2,3 mg
Vit C = 250 mg x 5 tab = 1250 mg/7= 178, 6 mg
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LATIHAN SOAL
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1
Tn. Stark harus meminum Captopril tablet 25 mg 1 kali sehari.
Sebelum ke luar negeri Tn. Stark membeli Captopril untuk
pemakaian 30 hari. Namun yang tersedia hanya Captopril 12,5
mg. Berapa yang harus disediakan untuk Tn. Stark dan
jelaskan bagaimana aturan pakainya!

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2
Nn. Zaskia mendapat resep Lincomycin 250 mg dengan aturan
pakai 2 kali sehari. Dokter menyarankan meminum obat
tersebut selama 4 hari. Berapa yang harus disiapkan untuk Nn.
Zaskia, jika Lincomycin yang tersedia 500 mg. Jelaskan aturan
pakainya!

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3
Acetyl salicylic acid 2,0
Phenil propanolamin 1,0
Caffein 1,0
SL qs Pertanyaan :
m.f pulv no.XII Jika dalam 1 bungkus harus berisi
S.t.dd pulv 1
500 mg. Berapa SL yang harus
ditambahkan?
Pro : Nn. Lily

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4
How many tablets of prednisolone 5mg should be dispensed to
a patient who has been prescribed prednisolone 25mg for 5
days?

125
25

50
5
45

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5
A patient has been prescribed naproxen 0.25g b.i.d. for 7 days.
Naproxen 500mg scored tablets are available. How may tablets
should be dispensed?

12
14

710
4

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6
The dose of diazepam for children in febrile convulsions is
250μg/kg. What is appropriate dose for a child weighing 25kg?

6.25mg
6250mg
62.5mg

625mg
10mg


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7
Calculate the weight in grams of 1 mole sulphate in calcium
sulphate (relative atomic mass of calcium = 40.08; sulphur =
32.07; oxygen = 16.00)

64
48

136
96
144

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8
The adult intravenous dose of gentamicin is 2mg/kg every 8
hours. How many milligrams will a 65kg patient receive daily?

1040mg
130mg
390mg

520mg
16mg


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9
Calculate the dose of a drug to be administered to a patient if
the dosing regimen is listed as 5mg/kg per day in divided doses
every 8 hours and the patient weighs is 67kg!

42mg t.d.d
67mg t.d.d

14mg t.d.d
335mg t.d.d
112mg t.d.d

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10
A pharmacist is required to dispense 30g of 0.5%
hydrocortisone ointment. The pharmacist has available a
hydrocortisone ointment 1%. How many grams of the 1%
ointment could be diluted with white soft paraffin to prepare this
order?

30g
15g
0.15g
0.5g
1.5g

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11
The amount of diclofenac that is being administered per tablet
of Voltarol tablet containing 25mg diclofenac sodium is :
(Diclofenac sodium has a molecular formula of
C14H10Cl2NO2.Na; relative atomic mass of carbon = 12.01;
hydrogen = 1.008; chlorine = 35.45; nitrogen = 14.01; sodium =
22.99; and oxygen = 16.00)

 20.99
23.19
21.98

25
24.27
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12
A woman with a body weight of 77kg is prescribed dapsone
2mg/kg daily. Dapsone is available as 50mg tablets. The
number of tablets to be dispensed for 30 days supply is:

 30
60
56
90

 100

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13
Rhinocort Aqua delivers 64 μg of budesonide per dose and
contains 120 doses. The amount of budesonide in mg per sack
is:

 0.064
76.8
7.68
768

 7680

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14
Each sachet of Dioralyte contain 0.47g sodium chloride and
0.30g potassium chloride. The amount in millimoles of chloride
in one sachet is (relative atomic mass of sodium = 23; chlorine
= 35; potassium = 39) :

0.12
0.012
4.05

12.15
8.10


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15
The amount in milligrams of hydrocortisone required to prepare
30g of hydrocortisone 0.1% w/w cream is:

0.003
0.0003

0.3
0.03
30


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Thank You! 
Any Questions?