Efisiensi Penggunaan Metode Tapping Smear Untuk

Mendeteksi Penyakit Mikosis Pada Hewan Kesayangan

Gledys Coornelia
17820003
 Pendahuluan
Penyakit fungal yang paling sering ditemukan pada hewan kesayangan adalah ringworm atau
dermatomikosis. Dermatomikosis menimbulkan penyakit kulit pada hewan kesayangan yang dapat menular pada
manusia (zoonosis). Dermatomikosis disebabkan oleh fungi keratinofilik yang dikenal dengan dermatofit, terdiri dari tiga
genus, yaitu Microsporum, Trichophyton, Epidermophyton.

Kapang dermatofita menginfeksi kulit bagian superfisial yang memiliki keratin seperti stratum korneum
pada epidermis kulit, rambut, kuku dan tanduk (Indarjulianto et al., 2017). Menurut Grondalen (2004) kejadian
dermatofitosis lebih sering terjadi pada kucing dibanding dengan anjing.

Kucing berusia dibawah empat bulan memiliki risiko lebih tinggi terinfeksi dermatofitosis, hal ini
disebabkan karena sistem kekebalan tubuh yang belum sempurna. Kucing dengan rambut panjang merupakan
predisposisi terjadinya dermatofitosis karena sel keratin lebih banyak pada rambut yang panjang daripada rambut pendek
(Indarjulianto et al., 2017).
Tanda dan gejala?
• bercak merah, bersisik, gatal atau timbul
• bercak mungkin lebih merah di tepi luar atau
menyerupai cincin
• bercak yang mulai mengeluarkan cairan atau
melepuh
• bercak botak bisa berkembang saat kulit kepala
terpengaruh
• kuku bisa menebal, berubah warna atau mulai
retak
 Penyebab

01 02
Antropolifilik Zoofilik
transmisi dari manusia ke transmisi dari hewan ke
manusia manusia

03
Geofilik
transmisi dari tanah ke inang
Diagnosis
01 Pengambilan sample
Sample diambil menggunakan
metode tapping smear
 Bagaimana caranya?
Mercury is the closest planet to the Sun and the smallest one in the Solar System—
it’s only a bit larger than the Moon. The planet’s name has nothing to do with the
liquid metal
02 Pewarnaan Sample
Pewarnaan menggunakan
 Pewarnaan

Preclinical Phase 1
Lab Studies Human Safety

Phase 2 Phase 3
Expanded Safety Efficacy & Safety
03 Identifikasi Sample
Identifikasi dilakukan dibawah
pengamatan mikroskop dengan
pembesaran 100x
 Identifikasi

Microsporum Trichophytonz Sporotricosis

Mercury is the closest Venus has a beautiful Despite being red, Mars is a
planet to the Sun and the Name. It’s the second cold place, not hot. The
smallest one planet from the Sun planet is full of iron
Treatment
The infection
What happens in the case of an
infection?
 Total Pasien di KHP

Desember 2020 Januari 2021 Februari 2021

Total 406 Pasien, 468 Pasien, 352 Pasien,
5 kasus mikosis 14 kasus mikosis 6 kasus mikosis

Maret 2021 April 2021

735 Pasien, - Pasien
17 Kasus mikosis 11 Kasus mikosis
234,456
Total pasien KHP
 Infection process
2. Barriers 4. Antibodies
Saturn is composed Neptune is the
mostly of hydrogen farthest planet

1. Bacteria 3. Helper T cells 5. Memory cells

Despite being red, Mars is Venus is the Jupiter is the biggest
cold second from the Sun planet in the System
 Immune factors to consider

Communicate Cause inflammation Strategic decisions

Kill enemies Activate other cells Remember enemies

Standby mode Produce antibodies Mark/disable enemies

 Phase 1
Secondary effects
Healthy people Venus has a beautiful name and
it’s the second planet from the
Sun

20 - 80 Participants Sample
30 - 40 Years old
Results
Earth is the planet where we
live and the only one known to
harbor life
 Cell example: The macrophage

Cause inflammation

Activate cells
Kill enemies

To modify this graph, click on it,

follow the link, change the data and
paste the resulting graph here
Communicate
 236,231
Here you can write some text about this number

8,469
Here you can write some text about this number

1,230
Here you can write some text about this number
 How does it start?

Rusty nail Your skin

It’s a beautiful day when The first barrier is broken,
suddenly a rusty nail appears nearby bacteria seize on the
and cuts you opportunity an enter
Growing the infection

Go, go, go!

Feeding with your body components, the bacteria

will reproduce until they double in number and
this is a big crowd to defeat
The defense to the attack

You’ll see!

Thanks to macrophages, the immune system

will be able to stop this invasion as fast as they
can
The macrophages’ defense

Next you will notice an inflammation, this is

because of the macrophages, which are defending
themselves thanks to the water released by your
blood vessels
The Neutrophils

Byeeee

To kill the bacteria you will need reinforcements!

For this reason, the macrophages bind to the
neutrophils that after fighting against the bacteria
will die
The dendritic cell

It is time for reinforcements, the dendritic cell is

provided with antibacterials to end the infection
with this backup
Dendritic cell Binding parts

Virgin helper T cell

To kill the invaders, the dendritic cell must join a T

cell, in this way they can kill the enemy and end
this infection
 Memory helper cell

T cells actives
Phase 1 Phase 2 Phase 3 Memory helper cell

Subject 1 315 285 600

When it joins with a helper T cell, it
begins the process of multiplying its
Subject 2 210 390 600 number, in this process some T cell will
be created, making you immune
Subject 3 240 165 580
 Stimulating cells
Keep going! Yeah!

T helper cell B cell

The B cells are activated by the group that These friends go too fast, luckily the T
moves to the lymph node. There will be cells are created to encourage them, in this
create the adequate tools to finish off the way they will end the infection of your
enemy body
 The antibodies
Antibody

B Cell

Then the blood is invaded by proteins

generated by B cells, these proteins bind to
the invader filling the body
 The helper T cells

I’m tired... Not now!

The infection has also progressed, multiplying in

number and invading the body. Guard cells fight
thanks to helper T cells that encourage them to
keep attacking
 Another line of defense

Then the second line of defense arrives, They also stun the bacteria and make them
millions of antibodies render or kill the an easy target connecting to killer cells
intruders in the process
Balance shifts
Bye friends!

The time to balance the damage has come , the

infection has been defeated and many cells have
lost their lives in the way, but now you are immune
and stronger!
 Memory cells

Memory helper T cell Memory B cell

These cells will be prepared to fight. In case the

enemy appears again they will attack it even before
you notice
Research and Publications

“Venus has a beautiful name

and it’s the second planet
from the Sun”

By Venus
“Despite being red, Mars is
actually a cold place full of
iron oxide dust”

By Mars
Research Resources
● Here you can list your reference websites or
publications
● Here you can list your reference websites or
publications
● Here you can list your reference websites or
publications
 Conclusions
Mercury is the closest planet to the Sun and the
smallest one in the Solar System—it’s only a bit
larger than the Moon. The planet’s name has
nothing to do with the liquid metal since it was
named after the Roman messenger god, Mercury
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 Resources
Photos Vectors
● Portrait of doctor posing at the hospital ● Virus collection
● Back view woman writing on blackboard ● Young people with virtual reality glasses
● Tubes in laboratory in flat design
● Flat colorful dynamic shapes backgroun
d
● Virus particles interacting with antibody
molecules
 Alternative Resources
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