PENDAHULUAN
Definisi
Dehidrasi adalah kondisi di mana tubuh kehilangan lebih banyak cairan daripada cairan yang
masuk dalam tubuh. Ketidakseimbangan ini juga mengganggu kadar garam, mineral, dan gula
dalam darah, yang dapat mengganggu fungsi tubuh dan menyebabkan efek yang berbahaya.
Dehidrasi dapat ditangani dengan mengurangi fator-faktor risiko. Diskusikan dengan dokter
untuk informasi lebih lanjut.
Demam
Diare lebih dari 2 hari
Produksi urin berkurang
Kebingungan
Kelemahan
Tidak dapat berkonsentrasi
Pingsan
Nyeri dada atau perut.
Jika Anda memiliki tanda-tanda atau gejala-gejala di atas atau pertanyaan lainnya,
konsultasikanlah dengan dokter Anda. Tubuh masing-masing orang berbeda. Selalu
konsultasikan ke dokter untuk menangani kondisi kesehatan Anda.
Penyebab
Apa penyebab dehidrasi?
Dehidrasi biasanya disebabkan oleh asupan cairan yang kurang. Faktor lainnya meliputi iklim,
aktivitas fisik, dan diet. Selain itu, dehidrasi dapat disebabkan oleh penyakit yang
mengakibatkan kehilangan cairan seperti diare, muntah, dan diabetes.
Faktor-faktor risiko
Apa yang meningkatkan risiko saya untuk dehidrasi?
Bayi memiliki risiko yang lebih besar terhadap dehidrasi, akibat berat badan yang rendah
membuat mereka sensitif terhadap kehilangan cairan meski sedikit.
Lansia juga berada dalam risiko yang lebih besar, karena mereka mungkin lupa atau tidak
menyadari bahwa mereka perlu minum cairan.
Orang-orang dengan penyakit kronis, seperti diabetes, penyakit ginjal, alkoholisme juga dapat
menderita dehidrasi.
Atlet, terutama pada acara yang memerlukan ketahanan seperti maraton, triatlon, dan turnamen
dapat terpengaruh akibat jumlah cairan tubuh yang hilang melalui keringat.
Orang-orang dengan profesi yang melakukan pekerjaan berat, seperti pekerja bangunan,
terekspos sinar matahari secara reguler, dan kehilangan banyak cairan dari keringat.
Ada beberapa gejala fisik yang dokter dapat digunakan dokter untuk mendiagnosis, seperti
disorientasi, tekanan darah rendah, debaran jantung cepat (palpitasi) demam dan kulit yang
tidak elastis.
Tes darah digunakan untuk mengetahui apakah ginjal berfungsi dengan baik atau tidak dan
untuk melihat kadar sodium, potasium, dan elektrolit lain pada tubuh.
Urinalisis sangat berguna untuk diagnosis dehidrisi, karena urin orang yang mengalami
dehidrasi akan tampak lebih gelap dan pekat.
Untuk menentukan dehidrasi pada bayi, dokter biasanya memeriksa soft spot (bagian yang
lunak) pada tengkorak, keringat, dan karakteristik otot tertentu.
Bayi dan anak-anak kecil dengan dehidrasi tidak boleh diberi air karena dapat mencairkan
kadar elektrolit dan mineral pada tubuh yang sudah rendah. Organisasi Kesehatan Dunia
(WHO) merekomendasi penggunaan cairan rehidrasi oral yang mengandung campuran
potassium, garam, dan gula untuk mengembalikan keseimbangan cairan tubuh.
Pada kasus dehidrasi yang parah, Anda perlu segera datang ke rumah sakit atau menghubungi
dokter untuk mendapatkan pengobatan yang tepat. Hal ini dapat meliputi pengobatan anti diare,
anti muntah, dan anti demam.
Pengobatan di rumah
Apa saja perubahan gaya hidup atau pengobatan rumahan yang dapat dilakukan untuk
mengatasi dehidrasi?
Berikut adalah gaya hidup dan pengobatan rumahan yang dapat membantu Anda mengatasi
dehidrasi:
Author Information
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Introduction
The World Health Organization defines dehydration as a condition that results from excessive
loss of body water. The most common causes of dehydration in children are vomiting and
diarrhea.
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Etiology
Infants and young children are particularly susceptible to diarrheal disease and dehydration.
Reason include higher metabolic rate, inability to communicate their needs or hydrate
themselves, and increased insensible losses. Other causes of dehydration may be the result of
other disease processes resulting in fluid loss which includes: diabetic ketoacidosis (DKA),
diabetes insipidus, burns, excessive sweating, and third spacing. Dehydration may also be the
result of decreased intake along with ongoing losses. In addition to total body water losses,
electrolyte abnormalities may exist. Infants and children have higher metabolic needs and that
make them more susceptible to dehydration.[1]
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Epidemiology
Dehydration is a major cause of morbidity and mortality in infants and young children
worldwide. Each year approximately 760,000 children of diarrheal disease worldwide. Most
cases of dehydration in children are the consequence of acute gastroenteritis.
Acute gastroenteritis in the United States is usually infectious in etiology. Viral infections,
including rotavirus, norovirus, and enteroviruses cause 75 to 90 percent of infectious diarrhea
cases. Bacterial pathogens cause less than 20 percent of cases. Common bacterial causes include
Salmonella, Shigella, and Escherichia coli. Approximately 10 percent of bacterial disease occurs
secondary to diarrheagenic Escherichia coli. Parasites such as Giardia and Cryptosporidium
account for less than 5 percent of cases.
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Pathophysiology
Dehydration causes a decrease in total body water in both the intracellular and extracellular fluid
volumes. Volume depletion closely correlates with the signs and symptoms of dehydration. The
total body water (TBW) in humans is distributed in two major compartments. 2/3rd the of TBW
is in the intracellular compartment and the other 1/3rd is distributed between interstitial space
(75%) and plasma (25%). The total body water is higher in infants and children as compared to
the adults. In infants, it is 70% of the total weight, whereas it is 65% and 60% respectively in
children and adults. As indicated earlier dehydration is total water depletion with respect to the
sodium and volume depletion is the decrease in the circulation volume. Volume depletion is seen
in acute blood loss and burns, whereas distributive volume depletion is seen in sepsis and
anaphylaxis. In much of the literature, the distinction between dehydration and volume depletion
is a blur.
Metabolic acidosis is seen in infants and children with dehydration, the pathophysiology of
which is multifactorial.
1. excess bicarbonate loss in the diarrhea stool or in the Urine is certain types of renal tubular
acidosis
2. Ketosis secondary to the glycogen depletion seen in starvation which sets in infants and
children much earlier when compared to adults.
3. Lactic acid production secondary to poor tissue perfusion
4. Hydrogen ion retention by the kidney from decreased renal perfusion and decreased
glomerular filtration rate.
In children with pyloric stenosis have very unique electrolyte abnormalities from the excessive
emesis of gastric contents. This is seen mostly in the older children. They loose chloride, sodium,
potassium in addition to volume resulting in hypochloremic, hypokalemic metabolic alkalosis.
Kidney excretes base in the form of Hco3 ion to maintain acid-base balance of loss of Hydrogen
ion in the emesis in the form of hydrogen chloride. It is interesting to note that kidney also
excretes hydrogen ion to save sodium and water, which could be the reason for aciduria.
Recently published article has shown that many children with pyloric stenosis may not have
metabolic alkalosis.
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Evaluation
Dehydration could be associated with hypo or hyper or isonatremia. Most cases of dehydration
are hyponatremic. In selected cases, electrolyte abnormalities may exist. This includes
derangements in sodium levels, acidosis characterized by low bicarbonate levels or elevated
lactate levels. For patients with vomiting, who have not been able to tolerate oral fluids
hypoglycemia may be present. Evaluation of urine specific gravity and the presence of ketones
can assist in the evaluation of dehydration.[3]
Children who were given free water when they have ongoing diarrhea disease can present with
hyponatremic dehydration, the excess of free water concurrent to excess sodium and bicarbonate
loss in diarrhea. This is also seen in the syndrome of inappropriate secretion of antidiuretic
hormone (SIADH). In these cases, the children appear to be more dehydrated and could also
present with hyponatremic seizure activity.
Similarly, infants who are fed oral rehydration solution prepared from excess salt or who lost
excess free water as in diabetes incipidus could have hypernatraemic dehydration
End-tidal carbon dioxide measurements have been studied in an attempt to assess degrees of
dehydration greater than five percent in children. This non-invasive approach has promise, but as
of now has not proven to be an effective tool in determining the degree of dehydration in
children. [4]
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Treatment / Management
Priorities in the management of dehydration include early recognition of symptoms, identifying
the degree of dehydration, stabilization, and rehydration strategies.
Symptoms include vomiting, diarrhea, fever, decreased oral intake, inability to keep up with
ongoing losses, decreased urine output, progressing to lethargy, and hypovolemic shock.
Mild Dehydration
The American Academy of Pediatrics recommends oral rehydration for patients with mild
dehydration. Breastfed infants should continue to nurse. Fluids with high sugar content may
worsen diarrhea and should be avoided. Children can be fed age-appropriate foods frequently but
in small amounts.
Moderate Dehydration
The Morbidity and Mortality Weekly Report recommends administering 50 mL to 100 mL of
oral rehydration solutions per kilogram per body weight during two to four hours to replace the
estimated fluid deficit, with additional oral rehydration solution, administered to replace ongoing
losses.
Severe Dehydration
For patients who are severely dehydrated, rapid restorations of fluids are required.
Patients who are severely dehydrated can present with altered mental status, lethargy,
tachycardia, hypotension, signs of poor perfusion, weak thread pulses, and delayed capillary
refill.
Intravenous fluids, starting with 20 ml/kg boluses of normal saline are required. Multiple boluses
may be needed for children in hypovolemic shock. Additional priorities include obtaining a point
of care glucose test, electrolytes, and urinalysis assessing for elevated specific gravity and
ketones. [5]
Hypoglycemia should be assessed at the point of care testing via glucometer, and venous blood
gas with electrolytes or serum chemistries. It should be treated with intravenous glucose. The
dose is 0.5 gm/km to 1 gm/km. This translates to 5 ml/kg to 10 ml/kg of D10, 2ml/kg to 4 ml/kg
of D25, or 1 ml/kg to- 2 ml/kg of D50. The use of D50 is usually reserved for an adolescent or
adult-sized patients using a large bore intravenous line.[6]
Replacement of Fluids
An assessment of the degree of dehydration will determine the fluid replacement. Using tables
that can predict the degree of dehydration is helpful. If a previous "well weight" is available, that
can be subtracted from the patient's "sick weight" to calculate total weight loss. One kilogram
weight loss equates to one liter of fluid lost.
The rate of replacement is based on the severity of the dehydration. Patients with hypovolemic
shock need rapid boluses of isotonic fluid either normal saline or ringer lactate at 20ml/kg body
weight. This could be repeated 3 times with reassessment in-between the boluses. Ringer lactate
is superior to normal saline in hemorrhagic shock requiring rapid resuscitation with isotonic
fluids.[7] This difference is not found in the children with severe dehydration from acute
diarrheal disease. In these children, the replacement with normal saline and ringer lactate did
show similar clinical improvement.[8]
Rapid infusion can cause cardiac insufficiency, congestive heart failure, and pulmonary edema.
Rapid correction in patients with diabetic ketoacidosis can cause cerebral edema in adolescent
and children.
The rate of replacement fluids is calculated after taking into account for the maintenance,
replacement and deficit requirement of the patient. Sodium requirements of the children in the
hospital are higher than that of the adults. The children have high metabolic needs, has higher
insensible lose as they have a higher body surface area. They also have higher respiratory and
heart rates, requiring the use of an intravenous solution containing high sodium like D5NS. The
deficit is determined by the degree of dehydration as outlined earlier. The second phase of fluid
replacement therapy lasts for 8 hours, during which the child requires 1/2 of the remaining deficit
in addition 1/3rd of the maintenance fluid. The remaining half of the deficit and the 2/3rd of the
daily maintenance therapy is given during the third phase of the therapy which spans the
following 16 hours.
Holliday-Segar calculation is used for calculation of maintenance fluid in children, which is
100ml/kg/day for first 10 kg body weight (BW), then 50 ml/kg/day for the next 10 kg BW and
then 20 ml/kg /day for any BW over and above.[9]
For patients where intravenous access can not be achieved or maintained, other methods can be
employed. They include continuous nasogastric hydration and subcutaneous hydration.[10]]
Hypodermoclysis refers to hydrating the subcutaneous space with fluid which can be absorbed
systemically. Hypodermoclysis is best reserved for the stable child or infant with mild to
moderate dehydration who either fails a trial of fluids by mouth or who needs some degree of
rehydration to facilitate gaining intravenous access after a slow subcutaneous fluid bolus has
been given.
The process begins with:
The placement of topical anesthetic cream, such as EMLA, cover with an occlusive dressing,
wait for 15 to 20 minutes.“Pinch an inch” of skin anywhere, but the most practical site for young
children is between the scapulae.Insert a 25-gauge butterfly needle or 24-gauge
angiocatheterInject 150 units hyaluronidase SC (if available).Infuse 20 mL/kg isotonic solution
over one hour, repeat as needed or use this technique as a bridge to intravenous access.
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Dehydration occurs when you use or lose more fluid than you take in, and your body
doesn't have enough water and other fluids to carry out its normal functions. If you don't
replace lost fluids, you will get dehydrated.
Anyone may become dehydrated, but the condition is especially dangerous for young
children and older adults.
The most common cause of dehydration in young children is severe diarrhea and
vomiting. Older adults naturally have a lower volume of water in their bodies, and may
have conditions or take medications that increase the risk of dehydration.
This means that even minor illnesses, such as infections affecting the lungs or bladder,
can result in dehydration in older adults.
Dehydration also can occur in any age group if you don't drink enough water during hot
weather — especially if you are exercising vigorously.
You can usually reverse mild to moderate dehydration by drinking more fluids, but
severe dehydration needs immediate medical treatment.
Symptoms
Thirst isn't always a reliable early indicator of the body's need for water. Many people,
particularly older adults, don't feel thirsty until they're already dehydrated. That's why it's
important to increase water intake during hot weather or when you're ill.
Listlessness or irritability
Adult
Extreme thirst
Dark-colored urine
Fatigue
Dizziness
Confusion
When to see a doctor
Diarrhea, vomiting. Severe, acute diarrhea — that is, diarrhea that comes on suddenly
and violently — can cause a tremendous loss of water and electrolytes in a short amount
of time. If you have vomiting along with diarrhea, you lose even more fluids and minerals.
Fever. In general, the higher your fever, the more dehydrated you may become. The
problem worsens if you have a fever in addition to diarrhea and vomiting.
Excessive sweating. You lose water when you sweat. If you do vigorous activity and
don't replace fluids as you go along, you can become dehydrated. Hot, humid weather
increases the amount you sweat and the amount of fluid you lose.
Risk factors
Anyone can become dehydrated, but certain people are at greater risk:
Infants and children. The most likely group to experience severe diarrhea and vomiting,
infants and children are especially vulnerable to dehydration. Having a higher surface area
to volume area, they also lose a higher proportion of their fluids from a high fever or burns.
Young children often can't tell you that they're thirsty, nor can they get a drink for
themselves.
Older adults. As you age, your body's fluid reserve becomes smaller, your ability to
conserve water is reduced and your thirst sense becomes less acute. These problems are
compounded by chronic illnesses such as diabetes and dementia, and by the use of
certain medications. Older adults also may have mobility problems that limit their ability to
obtain water for themselves.
People with chronic illnesses. Having uncontrolled or untreated diabetes puts you at
high risk of dehydration. Kidney disease also increases your risk, as do medications that
increase urination. Even having a cold or sore throat makes you more susceptible to
dehydration because you're less likely to feel like eating or drinking when you're sick.
People who work or exercise outside. When it's hot and humid, your risk of dehydration
and heat illness increases. That's because when the air is humid, sweat can't evaporate
and cool you as quickly as it normally does, and this can lead to an increased body
temperature and the need for more fluids.
Complications
Heat injury. If you don't drink enough fluids when you're exercising vigorously and
perspiring heavily, you may end up with a heat injury, ranging in severity from mild heat
cramps to heat exhaustion or potentially life-threatening heatstroke.
Urinary and kidney problems. Prolonged or repeated bouts of dehydration can cause
urinary tract infections, kidney stones and even kidney failure.
Seizures. Electrolytes — such as potassium and sodium — help carry electrical signals
from cell to cell. If your electrolytes are out of balance, the normal electrical messages can
become mixed up, which can lead to involuntary muscle contractions and sometimes to a
loss of consciousness.
Low blood volume shock (hypovolemic shock). This is one of the most serious, and
sometimes life-threatening, complications of dehydration. It occurs when low blood volume
causes a drop in blood pressure and a drop in the amount of oxygen in your body.
Prevention
To prevent dehydration, drink plenty of fluids and eat foods high in water such as fruits
and vegetables. Letting thirst be your guide is an adequate daily guideline for most
healthy people.
People may need to take in more fluids if they are experiencing conditions such as:
Vomiting or diarrhea. If your child is vomiting or has diarrhea, start giving extra water or
an oral rehydration solution at the first signs of illness. Don't wait until dehydration occurs.
Strenuous exercise. In general, it's best to start hydrating the day before strenuous
exercise. Producing lots of clear, dilute urine is a good indication that you're well-hydrated.
During the activity, replenish fluids at regular intervals and continue drinking water or other
fluids after you're finished.
Hot or cold weather. You need to drink additional water in hot or humid weather to help
lower your body temperature and to replace what you lose through sweating. You may
also need extra water in cold weather to combat moisture loss from dry air, particularly at
higher altitudes
Illness. Older adults most commonly become dehydrated during minor illnesses — such
as influenza, bronchitis or bladder infections. Make sure to drink extra fluids when you're
not feeling well.
Diagnosis
Your doctor can often diagnose dehydration on the basis of physical signs and
symptoms. If you're dehydrated, you're also likely to have low blood pressure, especially
when moving from a lying to a standing position, a faster than normal heart rate and
reduced blood flow to your extremities.
To help confirm the diagnosis and pinpoint the degree of dehydration, you may have
other tests, such as:
Blood tests. Blood samples may be used to check for a number of factors, such as the
levels of your electrolytes — especially sodium and potassium — and how well your
kidneys are working.
Urinalysis. Tests done on your urine can help show whether you're dehydrated and to
what degree. They also can check for signs of a bladder infection.
Treatment
The only effective treatment for dehydration is to replace lost fluids and lost electrolytes.
The best approach to dehydration treatment depends on age, the severity of
dehydration and its cause.
For infants and children who have become dehydrated from diarrhea, vomiting or fever,
use an over-the-counter oral rehydration solution. These solutions contain water and
salts in specific proportions to replenish both fluids and electrolytes.
Start with about a teaspoon (5 milliliters) every one to five minutes and increase as
tolerated. It may be easier to use a syringe for very young children. Older children can
be given diluted sports drinks. Use 1 part sports drink to 1 part water.
Most adults with mild to moderate dehydration from diarrhea, vomiting or fever can
improve their condition by drinking more water or other liquids. Diarrhea may be
worsened by full-strength fruit juice and soft drinks.
If you work or exercise outdoors during hot or humid weather, cool water is your best
bet. Sports drinks containing electrolytes and a carbohydrate solution also may be
helpful.
Children and adults who are severely dehydrated should be treated by emergency
personnel arriving in an ambulance or in a hospital emergency room. Salts and fluids
delivered through a vein (intravenously) are absorbed quickly and speed recovery.
You're likely to start by seeing your or your child's doctor. However, in some cases
when you call to set up an appointment, the doctor may recommend urgent medical
care. If you, your child or an adult who you care for is showing signs of severe
dehydration, such as lethargy or reduced responsiveness, seek immediate care at a
hospital.
If you have time to prepare for your appointment, here's some information to help you
get ready, and what to expect from the doctor.
What you can do
Write down any symptoms you or the person you're caring for is
experiencing, including any that may seem unrelated to the reason for which you
scheduled the appointment. If you or the person you're caring for has been vomiting or has
had diarrhea, the doctor will want to know when it began and how frequently it's been
occurring.
Write down key personal information, including any recent trips taken or foods recently
eaten that might have caused illness. In addition, your doctor will want to know if you or
the person you're caring for has recently been exposed to anyone with diarrhea.
Make a list of key medical information, including other conditions you or the person
you're caring for is being treated for and the names of the medications being taken.
Include on your list prescription and over-the-counter drugs, as well as any vitamins and
supplements.
I have other health conditions. Do I need to change the treatments I've been using for
them?
How recently have you urinated? Are you experiencing any pain or urgency with urination?
Do you also have other signs or symptoms, such as abdominal cramping, fever, headache
or muscle aches? How severe are these signs and symptoms?
Have you recently eaten any food that you suspect was spoiled?
Has anyone gotten sick after eating the same food that you did?
Have you recently been exposed to someone who you know was experiencing diarrhea?
Do you know what your or your child's weight was before symptoms started?
https://www.webmd.com/first-aid/dehydration-in-children-treatment diakses 17 februari 2019
WebMD Medical Reference Reviewed by Dan Brennan, MD on October 22, 2017
1. Call a Doctor
In young children, mild to moderate dehydration can happen very easily, particularly if the child
has diarrhea or is vomiting. Contact your child's pediatrician if your child:
2. Replace Fluids
For dehydration in an infant up to 1 year old:
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VIDEO
Effects of Dehydration
Dehydration is more than just being thirsty. Other signs are dry mouth, fatigue, headaches, and
dizziness.
Give extra fluids in frequent, small sips, especially if the child is vomiting.
Choose clear soup, clear soda, or Pedialyte, if possible.
Give popsicles, ice chips, and cereal mixed with milk for added water or fluid.
Continue a regular diet.
3. Follow Up
For mild dehydration, have your child rest for 24 hours and keep drinking fluids, even if
symptoms get better. Fluid replacement may take up to a day and a half. Continue on your
child's regular diet as well.
For severe dehydration, the child may need IV fluids in the hospital. If you feel that your child is
not improving or is getting worse, see your doctor right away.
Dehydration
Definition
Dehydration occurs when your body does not have as much water and fluids as it needs.
Dehydration can be mild, moderate, or severe, based on how much of your body's fluid is lost or not replaced. Severe
dehydration is a life-threatening emergency.
Alternative Names
Vomiting - dehydration; Diarrhea - dehydration; Diabetes - dehydration; Stomach flu - dehydration; Gastroenteritis -
dehydration; Excessive sweating - dehydration
Causes
You can become dehydrated if you lose too much fluid, do not drink enough water or fluids, or both.
You do not feel like eating or drinking because you are sick
You are nauseated
You have a sore throat or mouth sores
Older adults and people with certain diseases, such as diabetes, are also at higher risk for dehydration.
Symptoms
Thirst
Dry or sticky mouth
Not urinating much
Darker yellow urine
Dry, cool skin
Headache
Muscle cramps
Your health care provider will look for these signs of dehydration:
To treat dehydration:
For more severe dehydration or heat emergency, you may need to stay in a hospital and receive fluid through a vein
(IV). The provider will also treat the cause of the dehydration.
Dehydration caused by a stomach virus should get better on its own after a few days.
Outlook (Prognosis)
If you notice signs of dehydration and treat it quickly, you should recover completely.
Possible Complications
Death
Permanent brain damage
Seizures
Prevention
To prevent dehydration:
Drink plenty of fluids every day, even when you are well. Drink more when the weather is hot or you are
exercising.
If anyone in your family is ill, pay attention to how much they are able to drink. Pay close attention to children
and older adults.
Anyone with a fever, vomiting, or diarrhea should drink plenty of fluids. DO NOT wait for signs of
dehydration.
If you think you or someone in your family may become dehydrated, call your provider. Do this before the
person becomes dehydrated.
References
Kenefick RW, Cheuvront SN, Leon LR, O'brien KK. Dehydration and rehydration. In: Auerbach PS, Cushing TA,
Harris NS, eds. Auerbach's Wilderness Medicine. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 89.
Padlipsky P, McCormick T. Infectious diarrheal disease and dehydration. In: Walls RM, Hockberger RS, Gausche-Hill
M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice.9th ed. Philadelphia, PA: Elsevier; 2018:chap
172.