Diajukan untuk memenuhi tugas dan melengkapi salah satu syarat dalam menempuh
Program Pendidikan Profesi Dokter Bagian Ilmu Penyakit Dalam
di Rumah Sakit Umum Daerah Tugurejo
Disusun oleh :
Nuzul Zakila Ramadhani
H3A021068
Pembimbing :
dr. Hersa Donantya Daneswara, Sp.PD
Pembimbing
lain berusaha untuk menilai perawatan paliatif pada pasien usia lanjut dengan
keganasan hematologi195,196. Tak satu pun dari studi ini, bagaimanapun, adalah
khusus untuk pasien rawat inap. Satu percobaan Amerika saat ini mendaftar dan
bertujuan untuk mengevaluasi alat kecerdasan buatan untuk memprediksi
kebutuhan konsultasi perawatan paliatif spesialis selama rawat inap . Sebuah
197
2. Ferrell BR, Twaddle ML, Melnick A, et al. National consensus project clinical
practice guidelines for quality palliative care guidelines, 4th edition. J Palliat Med.
2018 Sep 4;21(12):1684–1689.
3. Crawley LM. Racial, cultural, and ethnic factors influencing end-of- life care. J
Palliat Med. 2005;8(Suppl 1):S58–69.
4. Olden AM, Holloway R, Ladwig S, et al. Palliative care needs and symptom patterns
of hospitalized elders referred for consultation. J Pain Symptom Manage.
2011;42(3):410–418.
5. Vincent GK, Velkoff VA The next four decades: the older population in the United
States: 2010 to 2050. US Department of Commerce, Economics and Statistics
Administration, US; 2010. (1138).
6. DeFrances CJ, Golosinskiy A, Hall MJ, et al. National hospital dis- charge survey;
2007 summary. 2010.
7. Chai E. Geriatric palliative care: a practical guide for clinicians. New York, NY:
Oxford University Press; 2014.
9. Saracino RM, Bai M, Blatt L, et al. Geriatric palliative care: meeting the needs of a
growing population. Geriatr Nurs. 2018 Mar-Apr;39 (2):225–229.
10. Evers MM, Meier DE, Morrison RS. Assessing differences in care needs and service
utilization in geriatric palliative care patients. J Pain Symptom Manage.
2002;23(5):424–432.
12. Lupu D, Quigley L, Mehfoud N, et al. The growing demand for hospice and
palliative medicine physicians: will the supply keep up? J Pain Symptom Manage.
2018 Apr;55(4):1216–1223.
13. Kamal AH, Bull JH, Swetz KM, et al. Future of the palliative care workforce:
preview to an impending crisis. Am J Med. 2017 Feb;130 (2):113–114.
14. Quill TE, Abernethy AP. Generalist plus specialist palliative care– creating a more
sustainable model. N Engl J Med. 2013 Mar 28;368 (13):1173–1175.
15. Carroll T, Weisbrod N, O’Connor A, et al. Primary palliative care education: a pilot
survey. Am J Hosp Palliat Care. 2018 Apr;35 (4):565–569.
16. Fail RE, Meier DE. Improving quality of care for seriously ill patients: opportunities
for hospitalists. J Hosp Med. 2018 Mar 1;13 (3):194–197.
17. Albers G, Froggatt K, Van den Block L, et al. A qualitative explora- tion of the
collaborative working between palliative care and geriatric medicine: barriers and
facilitators from a European perspective. BMC Palliat Care. 2016 May;11(15):47.
18. Gardiner C, Cobb M, Gott M, et al. Barriers to providing palliative care for older
people in acute hospitals. Age Ageing. 2011;40 (2):233–238.
19. Dy SM, Kiley KB, Ast K, et al. Measuring what matters: top-ranked quality
indicators for hospice and palliative care from the American Academy of Hospice
and Palliative Medicine and Hospice and Palliative Nurses Association. J Pain
Symptom Manage. 2015 Apr;49(4):773–781.
20. Kamal AH, Gradison M, Maguire JM, et al. Quality measures for palliative care in
patients with cancer: a systematic review. J Oncol Pract. 2014;10(4):281–287.
21. Dalkin SM, Lhussier M, Philipson P, et al. Reducing inequalities in care for patients
with non-malignant diseases: insights from a realist evaluation of an integrated
palliative care pathway. Palliat Med. 2016 Jul;30(7):690–697.
22. Coventry PA, Grande GE, Richards DA, et al. Prediction of appro- priate timing of
palliative care for older adults with non-malignant life-threatening disease: a
systematic review. Age Ageing. 2005 May;34(3):218–227.
23. Barkin RL, Barkin SJ, Barkin DS. Perception, assessment, treatment, and
management of pain in the elderly. Clin Geriatr Med. 2005 Aug;21(3):465–490.
24. Barbera L, Seow H, Husain A, et al. Opioid prescription after pain assessment: a
population-based cohort of elderly patients with cancer. J Clin Oncol.
2012;30(10):1095–1099.
25. Weissman DE, Meier DE. Identifying patients in need of a palliative care assessment
in the hospital setting: a consensus report from the Center to Advance Palliative
Care. J Palliat Med. 2011 Jan;14(1):17–23.
26. Ritchie CS, Kelley AS, Stijacic Cenzer I, et al. High levels of geriatric palliative care
needs in hip fracture patients before the hip fracture. J Pain Symptom Manage. 2016
Oct;52(4):533–538.
27. Loscalzo MJ. Palliative care: an historical perspective. Hematology Am Soc Hematol
Educ Program. 2008;1:465.
28. Periyakoil VS, Denney-Koelsch EM, White P, et al. Primer of Palliative Care. 7th ed.
Chicago, IL: American Association of Hospice and Palliative Medicine; 2019.
29. Hannon B, Swami N, Rodin G, et al. Experiences of patients and caregivers with
early palliative care: A qualitative study. Palliat Med. 2017 Jan;31(1):72–81.
30. Ferris FD, Balfour HM, Bowen K, et al. A Model to Guide Patient and Family Care.
J Pain Symptom Manage. 2002;24(2):106–123.
31. Ferris FD, Bruera E, Cherny N, et al. Palliative cancer care a decade later:
accomplishments, the need, next steps – from the American Society of Clinical
Oncology. J Clin Oncol. 2009 Jun 20;27(18):3052–3058.
32. Hawley PH. The bow tie model of 21st century palliative care. J Pain Symptom
Manage. 2014 Jan;47(1):e2–5.
34. Atreya S, Jeba J, Pease N, et al. Primary palliative care competency framework for
primary care and family physicians in India-Collaborative work by Indian
Association of Palliative Care and Academy of Family Physicians of India. J Family
Med Prim Care. 2019 8;Aug(8):2563–2567.
35. de Nooijer K, Pivodic L, Deliens L, et al. Primary palliative care for older people in
three European countries: a mortality follow-back quality study. BMJ Support Palliat
Care. 2019 Oct 16. [Epub ahead of print]
36. Ernecoff NC, Check D, Bannon M, et al. Comparing specialty and primary palliative
care interventions: analysis of a systematic review. J Palliat Med. 2019 Oct 23. [Epub
ahead of print]
37. Jacobsen J, Alexander Cole C, Daubman BR, et al. A novel use of peer coaching to
teach primary palliative care skills: coaching consultation. J Pain Symptom Manage.
2017 Oct;54(4):578–582.
38. Morrison RS, Penrod JD, Cassel JB, et al. Cost savings associated with US hospital
palliative care consultation programs. Arch Intern Med. 2008 Sep 8;168(16):1783–
1790.
39. Hanson LC, Usher B, Spragens L, et al. Clinical and economic impact of palliative
care consultation. J Pain Symptom Manage. 2008 Apr;35(4):340–346.
40. Jenkins CA, Schulz M, Hanson J, et al. Demographic, symptom, and medication
profiles of cancer patients seen by a palliative care consult team in a tertiary referral
hospital. J Pain Symptom Manage. 2000;19(3):174–184.
41. Deschodt M, Claes V, Van Grootven B, et al. Comprehensive ger- iatric care in
hospitals: the role of inpatient geriatric consultation teams. Brussels: Belgian Health
Care Knowledge Centre; 2015.
42. White SJ, Minick P. The perceptions of non–palliative care hospi- talist physicians
referring patients to a hospital palliative care program. J Hospice Palliative Nurs.
2016;18(1):39–45.
43. Rocque GB, Campbell TC, Johnson SK, et al. A quantitative study of triggered
palliative care consultation for hospitalized patients with advanced cancer. J Pain
Symptom Manage. 2015 Oct;50(4):462–469.
44. Hua MS, Li G, Blinderman CD, et al. Estimates of the need for palliative care
consultation across united states intensive care units using a trigger-based model. Am
J Respir Crit Care Med. 2014 Feb 15;189 (4):428–436.
45. Finkelstein M, Goldstein NE, Horton JR, et al. Developing triggers for the surgical
intensive care unit for palliative care integration. J Crit Care. 2016;35:7–11.
46. Lindvall C, Hultman TD, Jackson VA. Overcoming the barriers to palliative care
referral for patients with advanced heart failure. J Am Heart Assoc. 2014 Feb
28;3(1):e000742.
47. Arnold RM, Bailey FA, Billings JA, et al. Pioneer programs in palliative care: nine
case studies. New York, NY: Milbank Memorial Fund; 2000. p. 225.
48. Smith TJ, Coyne P, Cassel B, et al. A high-volume specialist palliative care unit and
team may reduce in-hospital end-of-life care costs. J Palliat Med. 2003 Oct;6(5):699–
705.
49. Connor SR. Development of hospice and palliative care in the United States.
OMEGA - J Death Dying. 2008;56(1):89–99.
50. Medicare C, Services M. Coverage of hospice services under hospi- tal insurance. In:
Medicare benefit policy manual. Baltimore, MD: CMS. 2004.
51. Kelley AS, Morrison RS. Palliative Care for the Seriously Ill. N Engl J Med. 2015
Aug 20;373(8):747–755.
52. Sha MC, Callahan CM, Counsell SR, et al. Physical symptoms as a predictor of
health care use and mortality among older adults. Am J Med. 2005 Mar;118(3):301–
306.
53. Chandra A, Crane SJ, Tung EE, et al. Patient-reported geriatric symptoms as risk
factors for hospitalization and emergency depart- ment visits. Aging Dis. 2015
6;Jun(3):188–195.
54. Rastogi R, Meek BD. Management of chronic pain in elderly, frail patients: finding a
suitable, personalized method of control. Clin Interv Aging. 2013;8:37–46.
55. Wijk H, Grimby A. Needs of elderly patients in palliative care. Am J Hosp Palliat
Care. 2008 Apr-May;25(2):106–111.
56. May P, Garrido MM, Cassel JB, et al. Cost analysis of a prospective multi-site cohort
study of palliative care consultation teams for adults with advanced cancer: where do
cost-savings come from? Palliat Med. 2017 Apr;31(4):378–386.
57. Gade G, Venohr I, Conner D, et al. Impact of an inpatient palliative care team: a
randomized control trial. J Palliat Med. 2008 Mar;11 (2):180–190.
58. Bruera E, Kuehn N, Miller MJ, et al. The Edmonton Symptom Assessment System
(ESAS): A simple method for the assessment of palliative care patients. J Palliat
Care. 1991;7(2):6–9.
60. Hui D, Bruera E. The edmonton symptom assessment system 25 years later: past,
present, and future developments. J Pain Symptom Manage. 2017 Mar;53(3):630–
643.
61. Pautex S, Berger A, Chatelain C, et al. Symptom assessment in elderly cancer
patients receiving palliative care. Crit Rev Oncol Hematol. 2003;47(3):281–286.
62. Walke LM, Byers AL, McCorkle R, et al. Symptom assessment in community-
dwelling older adults with advanced chronic disease. J Pain Symptom Manage. 2006
Jan;31(1):31–37.
63. Murray TM, Sachs GA, Stocking C, et al. The symptom experience of community-
dwelling persons with dementia: self and caregiver report and comparison with
standardized symptom assessment measures. Am J Geriatr Psychiatry. 2012
Apr;20(4):298–305.
65. O’Neill LB, Morrison RS, Arnold RM Palliative care: issues specific to geriatric
patients. UpToDate; 2016.
66. Fain KM, Alexander GC, Dore DD, et al. Frequency and predictors of analgesic
prescribing in U.S. nursing home residents with persis- tent pain. J Am Geriatr Soc.
2017 Feb;65(2):286–293.
67. Maxwell T. Cancer pain management in the elderly. Geriatr Nurs. 2000 May-
Jun;21(3):158–163.
68. Resnick B, Boltz M, Galik E, et al. Pain assessment, management, and impact among
older adults in assisted living. Pain Manag Nurs. 2019 Jun;20(3):192–197.
69. Wright R, Malec M, Shega JW, et al. Deconstructing Chronic Low Back Pain in the
Older Adult-Step by Step Evidence and Expert-Based Recommendations for
Evaluation and Treatment: part XI: dementia. Pain Med. 2016 Nov;17(11):1993–
2002.
70. Glare P, Miller J, Nikolova T, et al. Treating nausea and vomiting in palliative care: a
review. Clin Interv Aging. 2011;6:243–259.
71. Fried LP, Ferrucci L, Darer J, et al. Untangling the concepts of disability, frailty, and
comorbidity: implications for improved tar- geting and care. J Gerontol A Biol Sci
Med Sci. 2004 Mar;59 (3):255–263.
72. Boockvar KS, Meier DE. Palliative care for frail older adults: “there are things I
can’t do anymore that I wish I could ... “. JAMA. 2006 Nov 8;296(18):2245–2253.
73. Frenkel WJ, Jongerius EJ, Mandjes-van Uitert MJ, et al. Validation of the Charlson
Comorbidity Index in acutely hospitalized elderly adults: a prospective cohort study.
J Am Geriatr Soc. 2014 Feb;62 (2):342–346.
74. Buntinx F, Niclaes L, Suetens C, et al. Evaluation of Charlson’s comorbidity index in
elderly living in nursing homes. J Clin Epidemiol. 2002;55(11):1144–1147.
75. Portz JD, Kutner JS, Blatchford PJ, et al. High Symptom Burden and Low Functional
Status in the Setting of Multimorbidity. J Am Geriatr Soc. 2017 Oct;65(10):2285–
2289.
76. Wallis SJ, Wall J, Biram RW, et al. Association of the clinical frailty scale with
hospital outcomes. QJM. 2015 Dec;108(12):943–949.
77. Khandelwal D, Goel A, Kumar U, et al. Frailty is associated with longer hospital stay
and increased mortality in hospitalized older patients. J Nutr Health Aging.
2013;16(8):732–735.
78. Hubbard RE, Peel NM, Samanta M, et al. Frailty status at admission to hospital
predicts multiple adverse outcomes. Age Ageing. 2017 Sep 1;46(5):801–806.
79. Raudonis BM, Frailty: DK. An Indication for Palliative Care. Geriatric Nurs.
2010;31(5):379–384.
80. Reynolds K, Pietrzak RH, El-Gabalawy R, et al. Prevalence of psy- chiatric disorders
in U.S. older adults: findings from a nationally representative survey. World
Psychiatry. 2015 Feb;14(1):74–81.
81. Asghar-Ali AA, Wagle KC, Braun UK. Depression in terminally ill patients:
dilemmas in diagnosis and treatment. J Pain Symptom Manage. 2013
May;45(5):926–933.
82. Derogatis LR, Morrow GR, Fetting J, et al. The prevalence of psy- chiatric disorders
among cancer patients. Jama. 1983;249 (6):751–757.
83. Irwin SA, Rao S, Bower K, et al. Psychiatric issues in palliative care: recognition of
depression in patients enrolled in hospice care. J Palliat Med. 2008 Mar;11(2):158–
163.
84. Block SD. Assessing and managing depression in the terminally ill patient. Ann
Intern Med. 2000;132(3):209–218.
85. Stiefel F, Trill M, Berney A, et al. Depression in palliative care: a pragmatic report
from the Expert Working Group of the European Association for Palliative Care.
Support Care Cancer. 2001;9(7):477–488.
86. Barnes J, Kite S, Kumar M. The recognition and documentation of delirium in
hospital palliative care inpatients. Palliat Support Care. 2010 Jun;8(2):133–136.
87. Hosie A, Davidson PM, Agar M, et al. Delirium prevalence, inci- dence, and
implications for screening in specialist palliative care inpatient settings: a systematic
review. Palliat Med. 2013 Jun;27 (6):486–498.
88. Marcantonio ER. Delirium in hospitalized older adults. N Engl J Med. 2017 Oct
12;377(15):1456–1466.
89. LeGrand SB. Delirium in palliative medicine: a review. J Pain Symptom Manage.
2012 Oct;44(4):583–594.
90. Bruera E, Bush SH, Willey J, et al. Impact of delirium and recall on the level of
distress in patients with advanced cancer and their family caregivers. Cancer. 2009
May 1;115(9):2004–2012.
91. Leonard M, Agar M, Mason C, et al. Delirium issues in palliative care settings. J
Psychosom Res. 2008 Sep;65(3):289–298.
92. Agar MR, Lawlor PG, Quinn S, et al. Efficacy of oral risperidone, haloperidol, or
placebo for symptoms of delirium among patients in palliative care: a randomized
clinical trial. JAMA Intern Med. 2017 Jan 1;177(1):34–42.
94. Porche K, Reymond L, Callaghan JO, et al. Depression in palliative care patients: a
survey of assessment and treatment practices of Australian and New Zealand
palliative care specialists. Aust Health Rev. 2014 Feb;38(1):44–50.
95. Bakitas M, Lyons KD, Hegel MT, et al. Effects of a palliative care intervention on
clinical outcomes in patients with advanced can- cer: the Project ENABLE II
randomized controlled trial. JAMA. 2009 Aug 19;302(7):741–749.
96. Gwyther LP, Altilio T, Blacker S, et al. Social work competencies in palliative and
end-of-life care. J Soc Work End Life Palliat Care. 2005;1(1):87–120.
97. Massey K, Barnes MJD, Villines D, et al. What do I do? Developing a taxonomy of
chaplaincy activities and interventions for spiritual care in intensive care unit
palliative care. BMC Palliat Care. 2015 Apr 15;14(1):10.
98. Chochinov HM, Kristjanson LJ, Breitbart W, et al. Effect of dignity therapy on
distress and end-of-life experience in terminally ill patients: a randomised controlled
trial. Lancet Oncol. 2011;12(8):753–762.
99. Billings JA, Block SD. Integrating psychiatry and palliative medicine: the challenges
and opportunities. In: H. M. Chochinov, W. Breitbart, editors. Handbook of
psychiatry in palliative medicine. New York: Oxford University Press; 2009. p. 13–
22.
100. Meier DE, Beresford L. The palliative care team. J Palliat Med. 2008
Jun;11(5):677–681.
103. Hudson PL, Thomas K, Trauer T, et al. Psychological and social profile of
family caregivers on commencement of palliative care. J Pain Symptom Manage.
2011 Mar;41(3):522–534.
104. Hudson P, Remedios C, Zordan R, et al. Guidelines for the psycho- social
and bereavement support of family caregivers of palliative care patients. J Palliat
Med. 2012 Jun;15(6):696–702.
105. Wang X. Subjective well-being associated with size of social net- work and
social support of elderly. J Health Psychol. 2016 Jun;21 (6):1037–1042.
106. Bahramnezhad F, Chalik R, Bastani F, et al. The social network among the elderly
and its relationship with quality of life. Electron Physician. 2017 May;9(5):4306–
4311.
107. Scocco P, Nassuato M. The role of social relationships among elderly community-
dwelling and nursing-home residents: findings from a quality of life study.
Psychogeriatrics. 2017 Jul;17 (4):231–237.
108. Holt-Lunstad J, Smith TB, Baker M, et al. Loneliness and social isolation as risk
factors for mortality: a meta-analytic review. Perspect Psychol Sci. 2015
Mar;10(2):227–237.
109. Taylor HO, Taylor RJ, Nguyen AW, et al. Social isolation, depression, and
psychological distress among older adults. J Aging Health. 2018 Feb;30(2):229–
246.
110. Biddle KD, d’Oleire Uquillas F, Jacobs HIL, et al. Social engagement and amyloid-
β-related cognitive decline in cognitively normal older adults. Am J Geriatric
Psychiatry. 2019 May 10;27(11).
111. Ahluwalia SC, Chen C, Raaen L, et al. A systematic review in support of the
national consensus project clinical practice guidelines for quality palliative care,
fourth edition. J Pain Symptom Manage. 2018 Dec;56(6):831–870.
112. Puchalski CM. Spirituality in geriatric palliative care. Clin Geriatr Med.
2015;31(2):245–252.
113. Koenig HG. Religious attitudes and practices of hospitalized medi- cally ill older
adults. Int J Geriatr Psychiatry. 1998;13(4):213–224.
114. Hills J, Paice JA, Cameron JR, et al. Spirituality and distress in palliative care
consultation. J Palliat Med. 2005 8;Aug(4):782–788.
115. Balboni MJ, Sullivan A, Amobi A, et al. Why is spiritual care infre- quent at the
end of life? Spiritual care perceptions among patients, nurses, and physicians and
the role of training. J Clin Oncol. 2013 Feb 1;31(4):461–467.
116. Koenig HG, George LK, Titus P. Religion, spirituality, and health in medically ill
hospitalized older patients. J Am Geriatr Soc. 2004 Apr;52(4):554–562.
117. Chen H, Cheal K, McDonel Herr EC, et al. Religious participation as a predictor of
mental health status and treatment outcomes in older persons. Int J Geriatr
Psychiatry. 2007 Feb;22(2):144–153.
118. Pargament KI, Koenig HG, Tarakeshwar N, et al. Religious coping methods as
predictors of psychological, physical and spiritual out- comes among medically ill
elderly patients: a two-year longitudinal study. J Health Psychol. 2004
Nov;9(6):713–730.
119. Flannelly KJ, Handzo GF, Galek K, et al. A national survey of hospital directors’
views about the importance of various chaplain roles: differences among disciplines
and types of hospitals. J Pastoral Care Counsel. 2006;60(3):213.
120. Strang S, Strang P. Questions posed to hospital chaplains by palliative care patients.
J Palliat Med. 2002 Dec;5(6):857–864.
121. Piderman KM, Marek DV, Jenkins SM, et al., editors. Patients’ expectations of
hospital chaplains. Mayo Clinic Proceedings. 2008;83(1):58–DOI:10.4065/83.1.58
122. Puchalski C, Ferrell B, Virani R, et al. Improving the quality of spiritual care as a
dimension of palliative care: the report of the Consensus Conference. J Palliat Med.
2009 Oct;12(10):885–904. 123.
123. Cain CL, Surbone A, Elk R, et al. Culture and palliative care: pre- ferences,
communication, meaning, and mutual decision making. J Pain Symptom Manage.
2018 May;55(5):1408–1419.
124. Nelson A. Unequal treatment: confronting racial and ethnic disparities in health
care. J Natl Med Assoc. 2002;94(8):666–668.
125. Egede LE. Race, ethnicity, culture, and disparities in health care. J Gen Intern Med.
2006 Jun;21(6):667–669.
126. Rizzuto J, Aldridge MD. Racial disparities in hospice outcomes: a race or hospice-
level effect? J Am Geriatr Soc. 2018 Feb;66(2):407–413.
127. Horvat L, Horey D, Romios P, et al. Cultural competence education for health
professionals. Cochrane Database Syst Rev. 2014 5;May (5):CD009405.
128. Betancourt JR, Green AR, Carrillo JE, et al. Defining cultural compe- tence: a
practical framework for addressing racial/ethnic disparities in health and health
care. 433021. 2003 Jul-Aug;118(4):293–302.
129. Aggarwal NK. Reassessing cultural evaluations in geriatrics: insights from cultural
psychiatry. J Am Geriatr Soc. 2010 Nov;58 (11):2191–2196.
130. Ferrell BR. Spiritual, religious, and cultural aspects of care. New York, NY: Oxford
University Press; 2015.
132. Taylor EJ, editor Spirituality, culture, and cancer care. Seminars in Oncology
Nursing. 2001;17(3):197–205. DOI:10.1053/sonu.2001.25949
133. Lupton D. Medicine as Culture: illness, Disease and the Body. Thousand Oaks, CA:
SAGE Publications; 2012.
136. Long CO. Ten best practices to enhance culturally competent communication in
palliative care. J Pediatr Hematol Oncol. 2011;33:S136–S139.
137. Partain DK, Sanders JJ, Leiter RE, et al. End-of-life care for seriously ill
international patients at a global destination medical center. Mayo Clin Proc. 2018
Dec;93(12):1720–1727.
138. Epner DE, Baile WF. Patient-centered care: the key to cultural competence. Ann
Oncol. 2012;23(suppl 3):33–42.
139. Partain DK, Ingram C, Strand JJ. Providing appropriate end-of-life care to religious
and ethnic minorities. Mayo Clin Proc. 2017 Jan;92 (1):147–152.
140. Bloomer MJ, Botti M, Runacres F, et al. Cultural considerations at end of life in a
geriatric inpatient rehabilitation setting. Collegian. 2019;26(1):165–170.
141. Good MD, James C, Good BJ, et al. The culture of medicine and racial, ethnic, and
class disparities in healthcare. In: M. Romero, E. Margolis, editors. The Blackwell
Companion to Social Inequalities. Malden, MA: Blackwell Publishing, Ltd; 2005.
p. 396–423.
142. Lara M, Gamboa C, Kahramanian MI, et al. Acculturation and Latino health in the
United States: a review of the literature and its sociopolitical context. Annu Rev
Public Health. 2005;26:367–397.
143. Maddalena V, O’Shea F, Palliative MM. End-of-life care in new- foundland’s deaf
community. J Palliat Care. 2018;28(2):105–112.
144. Tuffrey-Wijne I. The palliative care needs of people with intellectual disabilities: a
literature review. Palliat Med. 2003 Jan;17(1):55–62.
145. Griebling TL. Sexuality and aging: a focus on lesbian, gay, bisexual, and transgender
(LGBT) needs in palliative and end of life care. Curr Opin Support Palliat Care. 2016
Mar;10(1):95–101.
147. Maingi S, Bagabag AE, O’Mahony S. Current best practices for sexual and gender
minorities in hospice and palliative care settings. J Pain Symptom Manage. 2018
May;55(5):1420–1427.
148. Whitford KJ, Hines SL, Bydon M, et al. Addressing the needs of international
patients at end of life in a tertiary care medical center. Mayo Clin Proc.
2018;93(12):1698–1699.
149. Martin DR. Challenges and opportunities in the care of interna- tional patients:
clinical and health services issues for academic medical centers. Acad Med.
2006;81(2):189–192.
150. Lorenz KA, Lynn J, Dy SM, et al. Evidence for improving palliative care at the end
of life: a systematic review. Ann Intern Med. 2008;148(2):147–159.
151. Pantilat SZ. End-of-life care for the hospitalized patient. Med Clin North Am.
2002;86(4):749–770.
152. Virdun C, Luckett T, Davidson PM, et al. Dying in the hospital setting: A systematic
review of quantitative studies identifying the elements of end-of-life care that patients
and their families rank as being most important. Palliat Med. 2015 Oct;29(9):774–
796.
153. Steinhauser KE, Christakis NA, Clipp EC, et al. Factors considered important at the
end of life by patients, family, physicians, and other care providers. JAMA. 2000
Nov 15;284(19):2476–2482.
154. El-Jawahri A, Greer J, Temel J. Does palliative care improve out- comes for patients
with incurable illness? a review of the evidence. J Supportive Oncol.
2011;05/01(9):87–94.
156. Hui D, Kim SH, Roquemore J, et al. Impact of timing and setting of palliative care
referral on quality of end-of-life care in cancer patients. Cancer. 2014 Jun
1;120(11):1743–1749.
157. Allen RS, Hilgeman MM, Ege MA, et al. Legacy activities as inter- ventions
approaching the end of life. J Palliat Med. 2008 Sep;11 (7):1029–1038.
158. Duggleby W, Wright K. Elderly palliative care cancer patients’ descriptions of hope-
fostering strategies. Int J Palliat Nurs. 2004 Jul;10(7):352–359.
159. Maltoni M, Scarpi E, Rosati M, et al. Palliative sedation in end-of-life care and
survival: a systematic review. J Clin Oncol. 2012 Apr 20;30 (12):1378–1383.
160. King M, Lodwick R, Jones R, et al. Death following partner bereavement: A self-
controlled case series analysis. PLoS One. 2017;12(3):e0173870.
161. Ornstein KA, Garrido MM, Siu AL, et al. An examination of down- stream effects of
bereavement on healthcare utilization for surviv- ing spouses in a national sample of
older adults. Pharmacoeconomics. 2019 Apr;37(4):585–596.
162. Shah SM, Carey IM, Harris T, et al. The effect of unexpected bereavement on
mortality in older couples. Am J Public Health. 2013 Jun;103(6):1140–1145.
163. Ott CH, Lueger RJ, Kelber ST, et al. Spousal bereavement in older adults: common,
resilient, and chronic grief with defining characteristics. J Nerv Ment Dis. 2007
Apr;195(4):332–341.
164. Shah SM, Carey IM, Harris T, et al. Initiation of psychotropic med- ication after
partner bereavement: a matched cohort study. PLoS One. 2013;8(11):e77734.
165. Arruda EH, Paun O. Dementia caregiver grief and bereavement: an integrative
review. West J Nurs Res. 2017 Jun;39(6):825–851.
167. Ghesquiere A, Thomas J, Bruce ML. Utilization of Hospice bereave- ment support
by at-risk family members. Am J Hosp Palliat Care. 2016 Mar;33(2):124–129.
168. Stephen AI, Wilcock SE, Wimpenny P. Bereavement care for older people in
healthcare settings: qualitative study of experiences. Int J Older People Nurs. 2013
Dec;8(4):279–289.
170. Dauwerse L, van der Dam S, Abma T. Morality in the mundane: specific needs for
ethics support in elderly care. Nurs Ethics. 2012 Jan;19(1):91–103.
171. Jox RJ, Schaider A, Marckmann G, et al. Medical futility at the end of life: the
perspectives of intensive care and palliative care clinicians. J Med Ethics.
2012;38(9):540–545.
172. Ko DN, Perez-Cruz P, Blinderman CD. Ethical issues in palliative care. Prim Care.
2011 Jun;38(2):183–193. vii.
173. Olsen ML, Swetz KM, Mueller PS. Ethical decision making with end-of- life care:
palliative sedation and withholding or withdrawing life-sustaining treatments. Mayo
Clin Proc. 2010 Oct;85(10):949–954.
174. Childers JW, Demme R, Greenlaw J, et al. A qualitative report of dual palliative
care/ethics consultations: intersecting dilemmas and paradigmatic cases. J Clin
Ethics. 2008;19(3):204–213.
178. Heyland DK, Barwich D, Pichora D, et al. Failure to engage hospitalized elderly
patients and their families in advance care planning. JAMA Intern Med. 2013 May
13;173(9):778–787.
181. Anderson WG, Chase R, Pantilat SZ, et al. Code status discussions between attending
hospitalist physicians and medical patients at hos- pital admission. J Gen Intern Med.
2011 Apr;26(4):359–366.
182. Detering KM, Hancock AD, Reade MC, et al. The impact of advance care planning
on end of life care in elderly patients: randomised controlled trial. BMJ.
2010;340:c1345.
183. Lum HD, Sudore RL, Bekelman DB. Advance care planning in the elderly. Med Clin
North Am. 2015 Mar;99(2):391–403.
184. Rietjens JAC, Sudore RL, Connolly M, et al. Definition and recommenda- tions for
advance care planning: an international consensus supported by the European
Association for Palliative Care. Lancet Oncol. 2017;18(9): e543–e551. 2017/09/01/.
185. Murray SA, Boyd K, Sheikh A, et al. Developing primary palliative care. BMJ. 2004
Nov 6;329(7474):1056–1057.
186. Muir JC, Arnold RM. Palliative care and the hospitalist: an opportu- nity for cross-
fertilization. Am J Med. 2001;111(9):10–14.
187. Pollak KI, Gao X, Beliveau J, et al. Pilot study to improve goals of care
conversations among hospitalists. J Pain Symptom Manage. 2019 Aug 16;58(5):864–
870.
188. Khateeb R, Puelle MR, Firn J, et al. Interprofessional rounds improve timing of
appropriate palliative care consultation on a hospitalist service. Am J Med Qual.
2018 Nov, Dec;33 (6):569–575.
189. Wald HL, Glasheen JJ, Guerrasio J, et al. Evaluation of a hospitalist-run acute care
for the elderly service. J Hosp Med. 2011 Jul-Aug;6(6):313–321.
190. Ahmed NN, Pearce SE. Acute care for the elderly: a literature review. Popul Health
Manag. 2010 Aug;13(4):219–225.
191. Hickman LD, Phillips JL, Newton PJ, et al. Multidisciplinary team interventions to
optimise health outcomes for older people in acute care settings: A systematic
review. Arch Gerontol Geriatr. 2015 Nov-Dec;61(3):322–329.
192. Advance Care Planning: Promoting Effective and Aligned Communication in the
Elderly (ACP-PEACE) (NCT03609177) ClinicalTrials.gov: National Library of
Medicine; [2019 Dec 1]. Available from:
https://clinicaltrials.gov/ct2/show/NCT03548142
193. A Geriatric Oncology Collaborative Care Intervention for Older Adults With
Advanced Cancer (NCT03721926) ClinicalTrials.gov: National Library of Medicine;
[2019 Dec 1]. Available from: https:// clinicaltrials.gov/ct2/show/NCT03721926
195. Study for Elderly (≥ 65 Years) Patients With Classical Hodgkin Lymphoma
Undergoing CGA at Diagnosis (NCT03552003) ClinicalTrials.gov: National Library
of Medicine; [2019 Dec 1]. Available from:
https://clinicaltrials.gov/ct2/show/NCT03552003
196. Early Palliative Care for Patients With Haematological Malignancies (CALVI)
(NCT03800095) ClinicalTrials.gov: National Library of Medicine; [2019 Dec 1].
Available from: https://clinicaltrials.gov/ ct2/show/NCT03800095
198. Effectiveness of the Supportive and Palliative Care Review Kit (SPARK) for Cancer
Patients in the Acute Hospital (NCT03330509) ClinicalTrials.gov: National Library
of Medicine; [2019 Dec 1]. Available from:
https://clinicaltrials.gov/ct2/show/NCT03330509