ABSTRACT
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to defects in
insulin secretion, insulin action or both. The purpose of this study is to explain the comparison of the effectiveness of
pharmacological therapy with pharmacological therapy accompanied by spiritual mindfulness based on breathing
exercise on anxiety levels and blood glucose levels in type 2 DM patients. This study is a quasi-experimental study
using a pretest-posttest design with control group design. . The sample size required for the study was 40 type 2 DM
patients who met the inclusion criteria. The sample was divided into two, 20 patients were used as the experimental
group who were given mindfulness-based spiritual therapy interventions on breathing exercise, 20 patients were used
as the control group. Samples were taken using purposive sampling technique and the sample size was determined by
the Slovin formula. Data collection techniques were carried out by administering a Hamilton Rating Scale For Anxiety
(HARS) questionnaire for data on anxiety levels and for blood glucose levels data were collected by measuring it
using a calibrated digital glucometer. Data analysis in this study used the Mann Whitney test, to compare the
effectiveness of pharmacological therapy with pharmacological therapy accompanied by spiritual mindfulness based
on breathing exercise on anxiety levels and blood glucose levels in type 2 DM patients. The results showed that there
were differences in the anxiety levels of patients in the group. control and experimental groups with a P-Value value
of 0.035 <0.05 and there are differences in blood sugar levels of patients in the control group and the experimental
group with a P-Value value of 0.003 <0.05. The conclusion of this study is that pharmacological therapy interventions
accompanied by spiritual mindfulness based on breathing exercise have been proven to be effective in reducing anxiety
levels and blood sugar levels in type 2 DM patients.
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