KELOMPOK 1:

A.A ISTRI DALEM CINTHYA RIRIS (01172465306)

AMALIA RATNA K. (011724653017)
NUR ANINDYA SYAMSUDI (011724653016)
RIMA WIRENVIONA (011724653012)
YOHANA DJURUMANA (011724653015)
 Sistem reproduksi wanita
dikendalikan dan dipengaruhi
oleh hormon-hormon
gonadotropin dan steroid, dari
poros hormonal hipotalamus,
pituitary, dan ovarium.

Perubahan hormonal terjadi

melalui mekanisme timbal balik
antara hipotalamus, pituitari, dan
ovarium yang dikenal
Hipothalamus , pituitary, Ovarium
Axis (HPO)
 SUMBU H – P – O

Hypothalamus
Long F.B Short F.B
Ultra Short FB
Hypothal.
GnRH

Neurotransmitter
(Down Reg.)

GnRH Pulsatile Secretion In

“Critical Range”

Pituitary
Inhibin B
Pituitary
FSH LH E&P
FSH & LH
E&P

Ovary

Foliculogenesis
Steroidogenesis
E P &
oogenesis
E&P

Ovulation
Menstruation

Speroff Leon and marca A Fritz. (2011). Clinical Gynecologic

Endocrinology and Infertility. Philadelphia, PA 19103 USA.
Hipothalamus Hipofisis
OVARIUM
 GnRH merangsang Hipofisis
anterior untuk memproduksi: • Fase folikuler
• Ovulasi
 FSH – Folicle Stimulating
• Fase luteal
Hormone
 LH – Luteinizing

H-P-O Aksis
Hormone

 Ovarium -> Steroidogenesis

(Estrogen dan Progesteron)
 -> Endometrium -> HAID
ENDOMETRIUM

• Fase proliferasi
• Fase sekretorik
• Fase Menstruasi

Speroff Leon and marca A Fritz. (2011). Clinical Gynecologic

Endocrinology and Infertility. Philadelphia, PA 19103 USA.
Reference

1. Speroff Leon and marca A Fritz. (2011). Clinical Gynecologic

Endocrinology and Infertility. Philadelphia, PA 19103 USA.
2. Nani, Desiyani. 2018. Fisiologi Manusia. Jakarta: Penebar
Swadaya Grup.